By Rajesh Kumar Singh
CHICAGO (Reuters) - Caterpillar Inc on Tuesday reported lower quarterly earnings as equipment sales fell across its three primary segments, reflecting a slow and uneven global economic recovery following lockdowns to curb the spread of the new coronavirus.
The heavy equipment maker, however, said the pace of decline in sales of its yellow bulldozers, mining trucks and other equipment was moderating, helped by a fast economic recovery in China and improvement in residential activity in North America.
I feel better today than I did a quarter ago, Chief Executive Jim Umpleby told investors on an earnings call, adding the pandemic and its impact on the global economy would determine the strength of the recovery.
The company did not provide an updated earnings guidance due to COVID-19 uncertainties. However, it said the decline in machine sales would moderate further in the quarter through December.
Operating profit is also forecast to improve in the current quarter from a quarter ago. Share repurchases, however, will remain suspended this year.
Caterpillar's shares were down 2.9% at $158.32 in morning trading. The stock has gained over 20% since the last earnings report, outperforming the broader Dow Jones Industrial Average, on hopes that the worst is over for its business.
The Illinois-based company, a bellwether for economic activity, has been suffering from business uncertainty caused by the U.S.-China trade standoff and the coronavirus pandemic, which has forced customers delay capital expenditure.
Chief Financial Officer Andrew Bonfield said while the demand for smaller machines has improved, customers were still hesitant to invest in heavy and more expensive equipment.
Reflecting weak equipment demand, Caterpillar now expects dealer inventories to decline by $2.5 billion this year compared with a more than $2 billion fall estimated earlier.
Profit for the third quarter came in at $1.22 per share, down 54% from a year ago, but above Refinitivs average analyst estimate of $1.16 per share. Retail sales declined 20% in the latest quarter, compared with a 23% drop a quarter ago.
Reporting by Rajesh Kumar Singh; Editing by David Holmes and Bernadette Baum.
Mexico City is the largest flexible office market in Latin America, with 11 percent of the market share by number of centers, while Buenos Aires is the most expensive, with a cost-per-desk of $570, according to a new report, The Growth of Agile Workspace: Latin America, by global workspace innovation firm The Instant Group.
Sigma America | 2020-21 Ambassadors The Sigma America Photo and Cine Ambassadors RONKONKOMA, N.Y., Oct. 27, 2020 (GLOBE NEWSWIRE) -- Sigma Corporation of America has officially announced its 2020-2021 roster of prestigious Sigma Ambassadors, a team of highly-talented, passionate photographers and cinematographers from across the geographic and demographic spectrum that will represent the company in a variety of areas, including online and virtual experiences, social media, traditional media, trade shows, in-store events, educational efforts and more. With wide-ranging expertise in a variety of genres and styles, Sigma Ambassadors are a unique group of individuals that not only demonstrate exceptional technical skills and artistry, but also embody the spirit of a company that continues to evolve and challenge the very concept of imaging, both as an art and as a business."Sigma is a family-owned company, and our Ambassadors are a special part of that family," says Mark Amir-Hamzeh, President of Sigma Corporation of America. "Together, we do our very best to provide creators around the country with the tools and inspiration they need. Our Ambassadors are an integral part of that mission, as they impart their expertise in a range of genres to enthusiasts and fellow professionals nationwide."Sigma Photo AmbassadorsMcKenzie DeakinsKnown for her relentless positivity and stunning wedding and engagement work, McKenzie is not only a talented woman behind the camera, she reminds us all why we inherently love photography because it's fun!mckenziedeakins.com@mckenziedeakinsAnabel DFluxVersatile and energetic, Anabel dove headfirst into photography as a career in her teenage years, and has since made a name for herself photographing show animals, musicians, concerts, and fantastical, gothic portraits.deliquesceflux.com@anabeldfluxLiam DoranThere's no backcountry trail, no rocky crevasse, no impenetrable snowdrift that will keep Liam from getting the perfect shot! Specializing in all things outdoors, Liam can teach you how to live off the land and take amazing photos of it, too.liamdoranphotography.com@liam_doran_outdoorsAdam ElmakiasTouring musicians don't have much time for rest, and neither does Adam, who travels alongside bands throughout the US and abroad, capturing them on stage and behind the scenes from dusk 'til whenever the bus gets to the next gig.adamelmakias.com@elmakiasMichelle HarrisRunning a wedding photography studio, shooting boudoir portraits and heading a national educational group seems like a lot, but apparently not for Michelle, who has made it her mission to "hustle 'til your haters ask if you're hiring!"mharrisstudios.com@mharris_studiosJim KoepnickThe professional's professional. Jim can shoot virtually anything, anywhere with any gear and find a story worth telling with incredible images to match. Sports, portraits, aviation, macro, landscapes the portfolio is endless!koepnickphotography.com@jim_koepnickMeg LoeksWith a style that is often imitated but never duplicated, Meg works her photographic magic with her family in rural Michigan where the four seasons and an impossibly cute quartet of kids make Meg's work a true joy to behold.megloeks.com@meg_nloMarla Michele MustMarla's eye-catching portrait work can be seen matted and framed in the homes of many Detroit-area families and dancers from all over the country, all of whom believe there is indeed something "enchanted" about her work!enchantedbymarlamichele.com@enchantedphotographymichiganBabak TafreshiDuring the day, Babak is a mild-mannered speaker and educator, but at night, he makes the most of what the night sky has to offer. From auroras on the very precipice of the world to the moon over Boston, Babak captures it all, much of it featured in National Geographic.babaktafreshi.com@babaktafreshiHiram TrilloUnique. Timeless. Unforgettable. Hiram's wedding albums are diverse and original, infused with his experience as a fashion photographer, making him a favorite from Texas to Spain and everywhere in between.hiramtrillo.com@hiramtrilloSigma Cine AmbassadorsTimur CivanOriginally driven by the eclectic and fast-paced environment of New York, Timur's techniques in cinematography are at the cutting edge of creative imaging, bolstered by his explorations with new and classic lenses, innovative lighting styles, and a deep dive into the latest tech.timurcivan.com@timurcivanChuck FranceTransitioning out of award-winning still photography and into cinematography, Chuck can create anything with a camera in hand. Currently, he works as a full-time freelance cinematographer on a wide variety of features, shorts and television.chuckfrance.com@chuckfranceMelinda JamesCentering her work on women, QTBIPOC, and underrepresented communities, Melinda is a cinematographer and filmmaker that is drawn to the process of unearthing the nuances of people's everyday lives.melindajamesdp.com@_melindajamesSherri KaukTender, defiant, and strikingly beautiful describes the work of Emmy Award winner Sherri Kauk. She has been involved in a number of highly-regarded productions, including the feature film LOEV, the Emmy-nominated Insecure, and documentary feature Akicita: The Battle of Standing Rock.sherrikauk.com@sherrikaukElle SchneiderSeen as both an artist and a creator, Elle is a cinematographer that specializes in narrative, branded films, and music videos. She also spent 5 years as the co-designer and creative director of Digital Bolex.elleschneider.com@attentionsoldierGraham SheldonDefining the term "one-man army", Emmy Award winner and PGA member Graham works all across the world as a producer and cinematographer. His clients include the likes of NBC, Vice, Disney, BBC, TLC and Discovery.grahamsheldon.net@grahamtesheldonSandra Valde-HansenRecognized as one of Variety's Artisans Up Next and ICG Generation Next Cinematographers, Sandra is currently shooting on the ground-breaking Showtime series The L Word: Generation Q.sandravalde.com@sandravaldeTo learn more about our Ambassador team, please visit: https://www.sigmaphoto.com/sigma-lounge/meet-the-ambassadorsFor media inquiries and bookings, please contact: email@example.comAbout Sigma CorporationCraftsmanship. Precision. Dedication. Since 1961, Sigma has been devoted to the pursuit of advancing photographic technology. Unique to the industry, the family-owned business produces its high-quality, award-winning still photo and cinema camera lenses, DSLR and mirrorless cameras, flashes, filters and accessories from its state-of-the-art manufacturing facility located in Aizu, Japan.In 2012, the company introduced Sigma Global Vision with three distinct lens lines: Art, Contemporary and Sports. Designed for industry camera mount systems including Canon, Leica, Nikon, Olympus, Panasonic, Sony and Sigma, each lens is handcrafted and tested in Japan to ensure a high-performance, premium product that is purpose-built to last. In 2016, the Sigma Cine lens lineup was launched, further cementing Sigma as an innovator in imaging engineering. Embodying the core optical DNA that has defined the Sigma benchmark of excellence, Sigma cine lenses meet the needs of advanced 6k and 8k cinema production.Forming the landmark L-Mount alliance alongside Leica and Panasonic in 2018, Sigma continues its storied tradition of imaging excellence through groundbreaking innovations such as the native L-mount SIGMA fp full-frame mirrorless digital camera, announced in July 2019. The introduction of the fp along with the availability of 20 award-winning Sigma Global Vision lenses in native L-Mount format demonstrates Sigmas continued commitment to the creative community through expanded product offerings. With the fp and these lenses, even more shooters can now leverage Sigmas renowned optical formula to achieve their creative vision with ease.For information about Sigma Corporation of America, please visit sigmaphoto.com and Sigma Blog for helpful information about our products.Follow Sigma Corporation of America on social media:Sigma Photo: Facebook, Twitter and Instagram.Sigma Cine: Facebook, Twitter and Instagram.Jack Howard / Sigma Corporation of America / firstname.lastname@example.orgA photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/cd2e8eb6-fbab-40a6-aab4-3386c272b890
SeriesRIKV 21 0517RIKV 21 0915 ISINIS0000032381IS0000032316 Maturity Date05/17/202109/15/2021 Auction Date10/29/202010/29/2020 Settlement Date11/02/202011/02/2020 On the Auction Date, between 10:30 am and 11:00 am, the Government Debt Management will auction Treasury bills in the Series, with the ISIN numbers and with the Maturity Dates according to the table above. Payments for the Treasury bills must be received by the Central Bank before 14:00 on the Settlement Date and the Bills will be delivered in electronic form on the same day.Further reference is made to the General Terms of Icelandic Treasury bills and General Terms of Auction for Treasury bills on the Government Debt Management website.For additional information please contact Oddgeir Gunnarsson, Government Debt Management, at +354 5699635.
Vave Health, maker of innovative handheld ultrasound technology, is addressing the prohibitive cost of medical imaging by offering clinicians and medical students a portable device to provide enhanced care no matter one's physical location or environmental barriers. With various subscription plans available, Vave Health provides a new model for imaging technology that is making ultrasounds more accessible to providers, patients, and today's rising medical professionals.
Paris, October 27, 2020 Atos SEs Ordinary General Meeting of shareholders was held today behind closed doors due to the sanitary constraints resulting from the COVID-19 epidemic. The General Meeting gathered to express an opinion on the Company's medium-term guidelines and to decide on the appointment of Edouard Philippe as a Director. The shareholders largely approved the resolutions presented.Atos SEs self-developed voting application based on blockchain technology was used by its employee shareholders for the second time.The General Meeting strongly supported the Company's medium-term guidelines, as approved by the Board of Directors on the proposal of the Chief Executive Officer (99.99%), thus confirming their relevance. The Meeting also approved the appointment of Edouard Philippe as Director with a very high rate (99.88%). The detailed results of the votes of the General Meeting are available on Atos website (Investors section General Meeting). ***Further to the first test carried out at the Annual General Meeting held on June 16, 2020, Atos SE has again made available to eligible employee shareholders its self-developed voting platform Atos Vote using blockchain technology, available on Android and iOS smartphones.Thanks to the work carried out in collaboration with Socit Gnrale Securities Services, the application Atos Vote that collects shareholders' voting instructions through this new secure and innovative transmission channel now exchanges this information with the centralizing bank.Atos Vote now offers voting shareholders, in addition to downloading a certificate of transmission of their voting instructions, the possibility to request confirmation that their vote has been taken into account.Atos is currently discussing with key players in the market a potential extension of the utilization of this application for the benefit of other users.Further information regarding the application Atos Vote is available on a dedicated page of Atos website.****About AtosAtos is a global leader in digital transformation with 110,000 employees in 73 countries and annual revenue of 12 billion. European number one in Cloud, Cybersecurity and High-Performance Computing, the Group provides end-to-end Orchestrated Hybrid Cloud, Big Data, Business Applications and Digital Workplace solutions. The Group is the Worldwide Information Technology Partner for the Olympic & Paralympic Games and operates under the brands Atos, Atos|Syntel, and Unify. Atos is a SE (Societas Europaea), listed on the CAC40 Paris stock index.The purpose of Atos is to help design the future of the information space. Its expertise and services support the development of knowledge, education and research in a multicultural approach and contribute to the development of scientific and technological excellence. Across the world, the Group enables its customers and employees, and members of societies at large to live, work and develop sustainably, in a safe and secure information space.ContactsInvestor Relations: Gilles Arditti - +33 1 73 26 00 66 -email@example.comPress: Sylvie Raybaud - +33 6 95 91 96 71 -firstname.lastname@example.orgAttachment * Atos Ordinary General Meeting
According to the new market research report "Digital Pathology Market by Product (Artificial Intelligence, Scanner, Software, Storage), Type (Human, Veterinary), Application (Teleconsultation, Disease Diagnosis, Drug Discovery), End-User (Pharmaceutical Companies, Hospitals) - Global Forecast to 2025", published by MarketsandMarkets, the Digital Pathology Market is projected to reach USD 1,054 million by 2025 from USD 553 million in 2020, at a CAGR of 13.8% during the forecast period.
Stenting is the mainstay in the treatment of intracranial stenosis and the subsequent conditions such as recurrent strokes. Further, worldwide prevalence of intracranial atherosclerosis has risen, propelling rapid technological advancements in the intracranial stents market. Need for improvement in flexibility of the stents opens new avenues.
The global Human Microbiome Therapeutics Market is forecast to be worth USD 1,098.4 Million by 2027, according to the latest analysis by Emergen Research. The human microbiome therapeutics market is forecast to augment rapidly due to the rising application of human microbiome therapeutics into personalized medicine and nutrition. Besides, the growing technological advancements in metagenomics and the therapeutic system is anticipated to further propel the market growth over the forecast timeframe.
Memberof the Board of Directors in Norsk Hydro ASA,Rune Bjerke has onOctober27, 2020 purchased 15 000 shares in Hydro at NOK 27.36 per share.New holding for Rune Bjerke is 15 000 shares.Investor contact: Line Haugetraa Head of Investor Relations +4741406376 email@example.com This information is subject to the disclosure requirements pursuant to Section 5-12 the Norwegian Securities Trading Act
The Law Offices of Frank R. Cruz announces that a class action lawsuit has been filed on behalf of persons and entities that purchased or otherwise acquired Portland General Electric Company ("PGE" or the "Company") (NYSE: POR) securities between April 24, 2020 and August 24, 2020, inclusive (the "Class Period"). PGE investors have until November 2, 2020 to file a lead plaintiff motion.
Verify Markets cites doTERRA as the singular reason for rapid market expansion, awards doTERRA with 2020 Verified Market Leader Award Verify Markets Global Aromatherapy and Essential Oils Market Report Verify Markets awards doTERRA as the 2020 Verified Market Leader and cites doTERRA as the singular reason for rapid market expansion.PLEASANT GROVE, Utah, Oct. 27, 2020 (GLOBE NEWSWIRE) -- doTERRA is the global leader in the essential oils and aromatherapy, substantiated once again by Verify Markets in its 2020 Global Aromatherapy and Essential Oils Market Report. In a recent press release, Verify Markets wrote, The global aromatherapy and essential oils market is undergoing rapid growth and evolving rapidly. doTERRA is well positioned to lead the market through increasing demands, requirements, demographics and trends shaping the market.Shipla Tiku, chief research officer at Verify Markets, said, doTERRA has been the singular reason for the rapid market expansion. doTERRA sells a lifestyle and values the customer as well as the importance of providing a valuable product. The company taps into an emotional part of the consumer that wants to aspire to live healthier. By identifying market gaps, doTERRA has quickly risen to global domination of the market.doTERRA attributes its growth to its incredible Wellness Advocates, customers, and employees. The company also ascribes its continuing leadership in the industry to its ongoing commitment to sourcing and providing verified pure products and remaining the most tested and most trusted essential oil company. doTERRA ensures that all stakeholders in the supply chain are implementing environmental stewardship and poverty solutions. The combination of doTERRAs product quality, vision for global sourcing solutions, scientific research and desire to give back, coupled with the growing health and wellness industry has catapulted the company to the forefront of the industry.We are grateful that Verify Markets industry analysis has identified so many factors that make doTERRA unlike any other company in the world, said David Stirling, doTERRA founding executive and CEO. Our mission is to empower through puritypure products, pure business practices, pure intention, and the pure love of humanity. Our growth and leadership in the industry is a direct result of how we do business. Through doTERRAs unique model, we support approximately 300,000 sourcing related jobs, which impacts almost 1.2 million lives, around the world and empower millions of people to take control of their health, wellness, and financial well-being.Learn more about Verify Markets 2020 Global Aromatherapy and Essential Oils Market research report.About doTERRAdTERRA International is an integrative health and wellness company and the world leader in the Global Aromatherapy and Essential Oils market. dTERRA sources, tests, manufactures and distributes CPTG Certified Pure Therapeutic Grade essential oils and essential oil products to over eight million dTERRA Wellness Advocates and customers. Through industry leading responsible sourcing practices, dTERRA maintains the highest levels of quality, purity and sustainability in partnership with local growers around the world through C-Impact Sourcing. The dTERRA Healing Hands Foundation, a registered 501(c)(3) non-profit organization, offers resources and tools to global sourcing communities and charitable organizations for self-reliance, healthcare, education, sanitation, and the fight against human trafficking. Through the life-enhancing benefits of essential oils, dTERRA is changing the world one drop, one person, one community at a time. To learn more, visit www.doterra.com.Contact: Kevin Wilson firstname.lastname@example.org A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/111f1a31-5145-48c3-a6e1-7748c77b3058
Riverview Financial Corporation ("Riverview") (NASDAQ: RIVE) has announced a companywide brand consolidation and a divisional name change initiative that will occur by the end of 2020. The name change will primarily affect offices in the Bank's western Pennsylvania footprint where it currently operates as CBT Bank and Citizens Neighborhood Bank. Beginning in 2021, all banking offices will operate as Riverview Bank.
Thanks to online sales, the major auction houses have found a way to continue to operate and countervail the Covid-19 health crisis. Lockdown forced them to activate the sudden and complete dematerialization of their most prestigious sales and their corresponding catalogs. This development one that has been a long time coming in the art market has allowed the bulk of secondary market fine art transactions to go ahead 'as normal', which in turn has substantially contributed to bolstering the confidence sellers need to consider consigning their works, and, a number of several quite remarkable performances have already been recorded.
Blackbaud (NASDAQ: BLKB), the world's leading cloud software company powering social good, is powering organizations with critical technology to support urgent fundraising efforts with Blackbaud CRM and in turn get those funds out to people who need them most with Blackbaud Grantmaking during the COVID-19 pandemic. With Blackbaud Grantmaking, organizations manage the entire grantmaking workflow, including applications, payments and communication with grantee partners, in one solution. Blackbaud CRM provides organizations with fundraising and relationship management software that integrates analytics, multi-channel marketing and data tools and services.
Manassas, VA, Oct. 27, 2020 (GLOBE NEWSWIRE) -- Eagle Health, LLC, a Cape Fox Corporation subsidiary, secured a three-year single-award, indefinite-delivery indefinite-quantity (IDIQ) contract to provide occupational health service support to the United States Army. Starting September 30, we bring a team of 73 providers including, Occupational Health Physicians, Occupational Health Nurses, Occupational Health Technicians, and Medical Support Assistants to support 32 Army Occupational Health Clinics located across the United States.Eagle Health is providing medical support to relieve the accumulation of occupational health examinations that occurred from the curtailment of non-essential occupational health services during the coronavirus disease pandemic. Our providers are responsible for performing examinations tailored to work-related requirements and potential hazards. Their work consists of reviews of medical histories, laboratory testing, immunizations, audiograms, vision testing, electrocardiograms, spirometry, radiology, fitness evaluations, record processing, and employee education.Eagle Health is proud to partner with the US Army to provide medical surveillance and screening services of Soldiers and Department of Army Civilians. We appreciate the continued opportunity to utilize our talent-first processes and systems to build and retain the workforce needed to advance the US Armys mission amid the COVID-19 crisis, said Harold Mitchell, President of Eagle Health.Eagle Health has always stood out from other companies for its exceptional professional services. Eagle Health is who is called upon for cutting edge medical services, adaptable solutions, and trusted experts who provide quick, effective solutions to the client. During these difficult times, Eagle health is proud to step in and step up to help our clients and provide the sought-after services many agencies require during this Pandemic.For additional information, email Heather Kaiser at email@example.com or call (703) 749-3045. About Cape Fox CorporationCape Fox Corporation (CFC) was formed as part of the Alaska Native Claims Settlement Act (ANCSA) of 1971. Cape Fox Corporation is the Alaska Native Corporation for the village of Saxman.Today, Cape Fox Corporation is comprised of a family of businesses divided between two distinct groups: The Federal Contracting Group and The Commercial Group. Collectively, CFC and its subsidiaries specialize in information technology and cybersecurity; professional services; health care services; marketing; training services; and logistical services.Visit Cape Fox Corporation to learn more. CONTACT: Heather Kaiser Cape Fox FCG 703.686.2340 firstname.lastname@example.org
Spain's left-wing government announced plans on Tuesday to raise taxes on large companies and high earners to fund increased spending on social care and infrastructure as part of its progressive agenda. With the coronavirus-battered economy expected to shrink an unprecedented 11.2% this year and tax revenues due to ebb 7.6%, the government aims to boost 2021 budget revenues by 6.8 billion euros ($8.04 billion), giving it more firepower to spend its way out of the crisis. Governments around the world have so far said very little about how they plan to pay for the cost of unprecedented levels of state support to virus-hit economies.
Merck was late to join the race to develop a vaccine to protect against the virus, which is again surging in many parts of the world including the United States. Rivals Pfizer Inc, AstraZeneca Plc and Moderna Inc are already deep into late-stage testing. The company began recruiting trial participants in September for an early-stage study of its COVID-19 vaccine candidate V591, which it acquired with the purchase of Austrian vaccine maker Themis Bioscience.
Tower Hill and Safeco announce a unique marketing partnership in the state of Florida between two non-affiliated carriers. Beginning in November, customers will have access to a multi-policy discount when they add a Tower Hill home to an account with a Safeco auto policy or add a Safeco auto policy to an account with a Tower Hill home policy. With market disruption commonplace in Florida, this is an opportunity for both companies to reach more customers through their multi-policy marketing partnership.
(Reuters) - U.S. industrial conglomerate 3M Co topped Wall Street estimates for quarterly profit on Tuesday, as the maker of N95 masks benefited from robust demand for its healthcare products during the COVID-19 pandemic.
There has been a recovery from last quarter when the company suffered a plunge in sales, as demand for office supplies declined with more people working from home due to the pandemic.
The company said the third quarter benefited from strong demand for personal safety and home improvement products.
Sales in its healthcare unit, which also makes surgical supplies and dental products, jumped 25.5%, and accounted for more than a quarter of the companys total sales.
However, the company said end markets for healthcare and oral care elective procedures continued to post year-on-year declines, mainly hit by the pandemic.
Sales at 3Ms transportation and electronics division, which also sells auto parts, fell 7.4%.
Net income attributable to 3M fell to $1.41 billion, or $2.43 per share, in the third quarter ended Sept. 30, from $1.58 billion, or $2.72 per share, a year earlier.
Net sales rose 4.5% to $8.35 billion.
Analysts on average had expected quarterly earnings of $2.26 per share on revenue of $8.32 billion, according to Refinitiv data.
Reporting by Sanjana Shivdas in Bengaluru; Editing by Shinjini Ganguli.
* Comprehensive preclinical package elucidates dual mode of action (MoA) and potential broad applicability of salt-inducible kinase (SIK)inhibitors in inflammation * Innovative chemistry generated multiple series of SIK compounds with distinct selectivity profiles, aimed at a range of inflammatory & fibrotic conditions * Phase 1 data with SIK2/3 selective GLPG3970 confirm dose-dependent dual MoA effect * Data package supports comprehensive clinical development of GLPG3970 in multiple Proof of Concept trialsMechelen, Belgium; 27 October 2020, 16.15 CET Galapagos NV (Euronext & NASDAQ: GLPG) unveils the Toledo target family as a series of salt-inducible kinase inhibitors. Toledo exhibits a dual mode of action characterized by enhanced transcription of anti-inflammatory cytokines and inhibited transcription of pro-inflammatory cytokines. Today, Galapagos also presents new preclinical and healthy volunteer data, and details its broad program to discover and develop multiple series of Toledo compounds with different selectivity profiles, aimed at treating a broad range of autoimmune conditions with important unmet medical need.The discovery of the SIK family of targets in our dual layer assays a number of years ago goes hand in hand with the scientific literature pointing to a dual mode of action of SIKs in inflammatory conditions, said Dr. Piet Wigerinck, Chief Scientific Officer at Galapagos. Galapagos developed innovative chemistry to address a number of selectivity profiles, and we now also show promising preclinical activity in fibrotic models, further broadening the scope of the Toledo program to a second disease paradigm where we built up substantial scientific know-how over the years. In the Phase 1 trial, we have shown a favorable PK profile and confirmed the dual mode of action, observing a dose-dependent effect in ex vivo healthy volunteers with GLPG3970.We generated the data package to take our first Toledo compound, GLPG3970, confidently into multiple proof of concept studies running in parallel. Currently the CALOSOMA study in psoriasis, the SEA TURTLE study in ulcerative colitis, and the LADYBUG study in rheumatoid arthritis are actively recruiting patients, and we aim to initiate two additional Phase 2 studies in Sjgrens and systemic lupus erythematosus early next year, said Dr. Walid Abi-Saab, Chief Medical Officer at Galapagos. Furthermore, we continue to take a programmatic approach, cross-learning from the different proof-of-concept studies and biomarkers in our comprehensive development plan. Building up our knowledge with rapid signal detection studies, we aim to understand as well as maximize the potential of our Toledo program to become a new paradigm in the treatment of inflammatory and fibrotic diseases. Our development strategy is aimed at optimizing the route of GLPG3970 to the market.About the GLPG3970 clinical portfolio CALOSOMA study: Phase 1 trial in psoriasis The Calosoma Phase 1 trial (NCT04106297) is a double-blind, placebo-controlled study evaluating the safety, tolerability, PK and PD1 of GLPG3970 single and multiple ascending doses in up to 52 adult healthy male subjects. GLPG3970 will now be investigated for 6 weeks in 25 subjects with moderate to severe psoriasis. The first patient was dosed recently.SEA TURTLE study: Phase 2 trial in ulcerative colitis (UC) This Phase 2 trial is a double-blind, placebo-controlled study evaluating the efficacy, safety, tolerability, PK and PD of GLPG3970 in up to 30 subjects with moderately to severely active UC. GLPG3970 or a placebo will be administered orally once daily for 6 weeks, with the primary endpoint of change from baseline in total Mayo Clinical Score (MCS). LADYBUG study: Phase 2 trial in rheumatoid arthritis (RA) This Phase 2 trial is a double-blind, placebo-controlled study evaluating the efficacy, safety, tolerability, PK and PD of GLPG3970 in up to 25 participants with severely active RA and an inadequate response to methotrexate. GLPG3970 or a placebo will be administered orally once-daily for 6 weeks, with the primary endpoint of change from baseline of DAS28 CRP at week 6. GLPG3970 is an investigational drug and its efficacy and safety have not been established.For information about clinical trials with GLPG3970: www.clinicaltrials.gov. For more information about the Toledo program: www.glpg.com/toledo-programAbout Galapagos Galapagos (Euronext & NASDAQ: GLPG) discovers and develops small molecule medicines with novel modes of action, several of which show promising patient results and are currently in late-stage development in multiple diseases. The companys pipeline comprises early discovery through to Phase 3 programs in inflammation, fibrosis, and other indications. Galapagos ambition is to become a leading global biopharmaceutical company focused on the discovery, development and commercialization of innovative medicines. More information at www.glpg.com.ContactsInvestors: Elizabeth Goodwin VP Investor Relations +1 781 460 1784Sofie Van Gijsel Senior Director Investor Relations +32 485 19 14 15 email@example.comMedia: Carmen Vroonen Global Head of Communications & Public Affairs +32 473 824 874Anna Gibbins Senior Director Therapeutic Areas Communications +44 7717 801900 firstname.lastname@example.orgForward-looking statementsThis press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, that are subject to risks, uncertainties and other factors that could cause actual results to dier materially from those referred to in the forward-looking statements and, therefore, the reader should not place undue reliance on them. These risks, uncertainties and other factors include, without limitation, the risk that ongoing and future clinical studies with GLPG3970 and other Toledo program molecules may not be completed in the currently envisaged timelines or at all, the inherent uncertainties associated with competitive developments, clinical trial and product development activities and regulatory approval requirements (including that data from the ongoing and planned clinical research programs may not support registration or further development of GLPG3970 and other Toledo program molecules due to safety, efficacy or other reasons), and that Galapagos estimations regarding the mode of action of GLPG3970 and other Toledo program molecules, regarding its GLPG3970 and other Toledo program molecules development program and regarding the commercial potential of GLPG3970 and other Toledo program molecules, may be incorrect, as well as those risks and uncertainties identified in our Annual Report on Form 20-F for the year ended 31 December 2019 and our subsequent filings with the SEC. All statements other than statements of historical fact are statements that could be deemed forward-looking statements. The forward-looking statements contained herein are based on managements current expectations and beliefs and speak only as of the date hereof, and Galapagos makes no commitment to update or publicly release any revisions to forward-looking statements in order to reflect new information or subsequent events, circumstances or changes in expectations.* * * 1 Pharmacokinetics and pharmacodynamics Attachment * Galapagos R&D Roundtable showcases Toledo program
IMPORTANT ALERT FROM FIRM THAT FILED THE LAWSUIT: The Schall Law Firm Announces the Filing of a Class Action Lawsuit Against Nikola Corporation and Encourages Investors with Losses in Excess of $500,000 to Contact the Firm
LOS ANGELES, CA / ACCESSWIRE / October 27, 2020 / The Schall Law Firm, a national shareholder rights litigation firm, announces the filing of a class-action lawsuit against Nikola Corporation ("Nikola" or "the Company") (NASDAQ:NKLA) for violations of 10(b) and 20(a) of the Securities Exchange Act of 1934 and Rule 10b-5 promulgated thereunder by the U.
USD TENDER OPERATION ANNOUNCEMENTUSD TENDER OPERATION ANNOUNCEMENT OCT 29, 2020Transaction type:Reverse Transaction Operation type:Liquidity providing Tender date:OCT-29-2020 Time for submission of bids14.00-14.30 (CEST) Start date:NOV-2-2020 Maturity date:JAN-25-2021 Duration:84 days Offered volume:10.0 bln Min bid amount:100 mln Maximum bid amount:4.0 bln Max number of bids:10 Lowest interest supplement:0.25 percentage points Min bid rate:t.b.a. Allocation time:15.00 (CET) on Tender date Approved counterparties are invited to submit bids to the Riksbank, tel +46 8 6966970 by 14.30 (CET) on October 29, 2020. Confirmation of bids to e-mail: email@example.com
Over at The Atlantic, Yascha Mounk argues that a vote for Joe Biden is a vote against the illiberal Left. Dont like Antifa, or the woke ideologies that seek to silence democratic debate, and transform liberal institutions into ideological hothouses? Well, then Joes your man. The illiberal Left is empowered in Trumps America, says Mounk, but it will surely wither before the awesome power of moderate Democrats.Now, there is always a plausible element of the arguments that suggest a moderate concession will avoid the perils of extremism. Republicans sometimes made a version of this when they said that theyd have gotten a little bit of protective trade action against China, and a little bit more border enforcement, if only Democrats could have accepted Mitt Romney and his binders full of women. Theyd have stopped the party from lurching toward Trump.But there are a few problems with Mounks case. He doesnt mention some obvious things. Take, for example, the fact that Donald Trump is defunding the indoctrination of federal employees in the illiberal left-wing ideology of critical race theory. Yet, even rather moderate organs such as *the Washington Post* treat this as perverse behavior, which leads me to believe that a President Biden would likely restore funding to them.But more seriously, Mounk doesnt describe the illiberalism on the left with any rigor. He merely says that the illiberal Left makes two intellectual mistakes. The first, he writes is to focus so tightly on the countrys flaws that its strengths become invisible, and its institutions dispensable. The second is to believe that the Right poses such an imminent danger that any form of resistance against it is justifiable, even if it involves violence.But this excessively dark view of the American project and its political institutions predated Trump. Although it has roots in radical 20th-century ideologies, its rise in prominence dates to the second term of the Obama administration, perhaps because of some disappointment that the Obama administration did not bring the kind of change some progressive hoped for. This pessimism is no clearer than in the writings of Ta-Nehisi Coates. And a foreshadowing of this current summers unrest and its relationship to progressive politics is evident in Baltimore mayor Stephanie Rawlings-Blakes decision to [give] those who wished to destroy space to do that as well.Although the violence associated with Antifa does excite opposition, the primary objective of the Rights resistance is toward the illiberal Lefts mostly legal forms of social repression, indoctrination, and bolder attacks against equality before the law.The social repression includes outrage and pressure campaigns to deprive dissenters (often people not known for political conflict) of their livelihoods and social reputations (e.g., Brendan Eich, James Damore). They fear that the illiberal Left will increasingly capture and weaponize the existing sensitivity-training structures, and the attached Title VIIlitigation machine, to make adherence -- or at least submission -- to their political doctrines semi-compulsory for employment across huge sectors of the economy.The Right would like to resist the spread of illiberal-Left indoctrination into educational institutions. Countless parents will have received anti-racist statements inspired by Ibram X. Kendi from their local K-12 public school districts this year. Many others will have noticed that the illiberal Left could assemble for protests and riots without being in danger of punishment for violating public-health restrictions this summer. Generally applicable restrictions and public shaming were imposed on, say, religious congregations, but were mysteriously lifted for the illiberal Left.Mounks description of the political relationship between his center-left colleagues and the illiberal Left undercuts his argument. Mounks new project, Persuasion, is grounded in an unshakeable commitment to liberal democracy and free speech. But the existence of an objectionable figure on the Right -- in this case, Trump -- just makes those commitments too difficult. For Mounk, Trumpian provocation makes it much harder for establishment institutions, as well as moderate voices on the left, to hold their ground.So Mounk, thinking of No. 1, asks conservatives to give up all the priorities they dont share with him, because a Biden victory would make it easier, not harder, to push back against Antifa types who think engaging in violent tactics to resist the Trump administration is justifiable.But, again this misunderstands the challenge of the illiberal Left, which is not merely reducible to Antifa. In the real world, what we find is that it is never easy enough for the center-left to resist the hard Lefts demands. Look at the trouble James Bennet found at the New York Times. After running an op-ed by Arkansas Republican senator Tom Cotton, he could only be protected by the institutional liberals for a few hours. And, after enduring a day-long struggle session, he was still fired. Even in those liberal institutions that have absolutely thrived during the Trump era, liberal institutionalists can protect moderate dissenters from the new orthodoxy for about 2448 hours before giving in to the illiberal Left within.The mistake is in viewing the illiberal Lefts rise as part of some thermostatic response to Trumpism -- a fever that will subside when the irritant is gone. But the illiberal Lefts rise is structural. The current trajectory is one of consolidation.It is unthinkable to imagine Mounk writing a column explaining that the existence of Antifa or of cancel culture makes it just too difficult for him to condemn or resist the populist Right, and that he cant confront the Right until the illiberal Left goes away.Voting Trump is unlikely to break the back of the illiberal Left. But lets not give in to the self-flattering bravery of moderate liberals, who can stand up for free speech until the exact moment a conservative makes it too difficult.
Available to All Heavy Work Industry Partners and Friends for the Months of November and DecemberBIRMINGHAM, Ala., Oct. 27, 2020 (GLOBE NEWSWIRE) -- Command Alkon, the Leading Supplier Collaboration Platform for Constructions Heavy Work, announces two free months of ELEVATE content delivered online. The virtual ELEVATE Awards Ceremony on October 28th at 12 PM CDT will kick off this digital learning experience for members of Command Alkons community of customers and partners from all around the world. Although we wont be together at the Hard Rock Hotel & Casino as originally planned, we are still looking forward to providing content of value to the industry and to our system users, said Lori Allen, Director of Corporate Marketing at Command Alkon. All of this content is free to our customers and industry partners as we work together to wrap up a very unique 2020.The ELEVATE online content schedule will begin the week of November 2nd and continue through to the week of December 14th. One to two sessions will be available each day for attendees to choose from: * PowerTalks covering industry trends, leadership topics, and success stories from the field. * User Community Workshops providing a forum for users to share product feedback, needs, and share best practices. * Innovation Zones highlighting new tech, new features and functions, and product training topics of interest. For a detailed schedule of online sessions and registration, visit the event website.ABOUT COMMAND ALKONAs the provider of the leading Supplier Collaboration Platform for Heavy Work, Command Alkon solutions deliver supply chain digital collaboration across the heavy construction community. CONNEX, a technology platform built for the industry, enables business partners to automate and integrate business process, capture real-time visibility into heavy material orders and deliveries, and share knowledge to promote certainty of outcomes. Command Alkon is headquartered in Birmingham, Alabama and has offices in locations around the globe. For more information, visit commandalkon.com.For More Information, Contact:Karli Langner Command Alkon (205) 879-3282 x 3968 firstname.lastname@example.org
Enthusiasts who can't wait to put donut doors on their 2021 Ford Bronco will need to find an aftermarket solution, according to a recent report. Although middle-less doors were shown on some of the Blue Oval's early prototypes, insiders confirmed that safety-related hurdles will prevent this feature from reaching production. Bronco owners recently convened in the Great Smoky Mountains for a trip on and off the beaten path, and Ford sent several representatives to the event.
The partnership, which plans to launch the rides in the first half of 2021, aims to combine Motional's driverless vehicles with Via's technology that powers booking, routing, passenger and vehicle assignment. Last week, Motional said it would resume its self-driving mobility service with Lyft in Las Vegas after pausing operations due to the COVID-19 pandemic.
Innovative BioPharma (IBP), a leader in pharmaceutical, bioscience, and nutrition medical communication and education has expanded to launch, The Endocannabinoid and Metabolic Health Group (EMHG), including its online education platform featuring live and virtual programming for all clinicians seeking education about the endocannabinoid system (ECS).
Removery, the world's largest tattoo-removal chain, is expanding in the Midwest and Northeast regions of the U.S. to meet market demand. It acquired Chicago and Milwaukee-based Vamoose Tattoo Removal, which joins the company's expansive laser specialist team. Removery has also announced new locations in King of Prussia, Pennsylvania, and Burlington, Massachusetts, bringing their number of locations to 40 across the U.S. and Canada, with 200 additional locations slated to open internationally by 2025.
IMPORTANT DEADLINE ALERT FROM FIRM THAT FILED THE LAWSUIT: The Schall Law Firm Announces the Filing of a Class Action Lawsuit Against LexinFintech Holdings Ltd. and Encourages Investors with Losses in Excess of $100,000 to Contact the Firm
SANTA BARBARA, Calif., Oct. 27, 2020 (GLOBE NEWSWIRE) -- ClarionDoor, provider of the industrys most intelligent insurance product distribution platform, is pleased to announce that Breckenridge Insurance Services (Breckenridge), a Texas-based wholesale managing general agent (MGA) that offers coverages for property and casualty (P&C) markets throughout the U.S., has selected the ClarionDoor MGA Hub (CD MGA Hub) to handle the companys commercial general liability and property business. Breckenridge, founded in 2009, specializes in program business and extensive offerings for P&C insurance sold through independent agents across the country. As the company continues to expand operations, a modern, digital distribution platform was needed to respond to the needs of an ever-changing marketplace.Evaluating pricing across all market options is extremely critical in todays market conditions, said Trevor Pierce, president of Breckenridge. Obtaining pricing from multiple insurance companies can be very time consuming, especially with renewals, and our underwriters needed an interface that could streamline that entire process. This is one of the major reasons why we chose ClarionDoor.The CD MGA Hub is a technological breakthrough that enhances the MGA experience by utilizing a simple interface to connect MGAs with multiple insurance companies in real-time. Underwriters gain the advantage of instant market appetite, comparative carrier indications, and push-to-carrier capabilities which reduce the overall time involved in evaluating market pricing.We built the CD MGA Hub to provide those efficiencies that MGAs desperately need, said Pat McCall, chief sales officer at ClarionDoor. On average, underwriters can spend hours evaluating price options from multiple carrier portals, and often, opportunities get missed. CD MGA Hub streamlines that entire process enabling underwriters to evaluate carrier options instantly. We are looking forward to delivering these kinds of underwriting and operational efficiencies for Breckenridge.Launched earlier this year, and with more than fifteen MGAs using the platform, ClarionDoors MGA Hub is changing MGA quoting processes. For more information, please contact Spiro Skias, Director of Product Marketing at ClarionDoor, at email@example.com, or visit the company website at www.clariondoor.com.About Breckenridge Insurance Services (Breckenridge) Breckenridge Insurance Services (Breckenridge) is a national wholesale insurance brokerage/MGA delivering top-rated, competitive commercial coverage solutions. With more than three decades of providing responsive counsel and risk management insights, Breckenridge has become a recognized leader and trusted partner to valued agents and coveted carrier partners internationally. With significant in-house contract binding authority and expert, award-winning brokers spanning nearly all property and casualty, workers compensation and professional liability risks, we offer collaborative, comprehensive solutions. As part of Breckenridge Insurance Group, the team has access to additional resources and expertise to help clients go further. For more information, please visit WWW.BRECKIS.COM. About ClarionDoor ClarionDoor is disrupting how the insurance industry distributes insurance via an API-first, cloud native, intelligent product distribution platform where you can rate, quote, bind, issue, and track business performance. Built for ongoing innovation, sales, and distribution, ClarionDoors platform is designed for any product, line of business, and geography. Our breakthrough technology has enabled MGAs, brokers, and carriers to go live in weeks and focus more on innovation rather than implementation. ClarionDoors proven track record of delivering on time is backed by zero failed projects and 100% referenceable clients. Learn more at clariondoor.com or contact us at firstname.lastname@example.org.
Certent, Inc., a leading provider of software-as-a-service solutions for financial disclosure management and equity compensation, announced today Certent is a leader in the G2 Grid Fall 2020 Report for Equity Management. The report spotlights equity management solutions that simplify and streamline all the crucial aspects of stock administration and reporting. Certent received the highest overall customer satisfaction score. The high marks can be directly attributed to the dedication and focus that Certent places on customer satisfaction in their daily business practice. Nearly 85% and counting of Certent's support staff have received their CEP certification. A crucial achievement for anyone who wants to understand stock plan best practices. Certent also consistently receives high scores for quality of support, ease of doing business, and meeting customer requirements.
Fred Haas is proud to celebrate 50 years serving the automotive needs of Houston, Texas, and beyond. Fred Haas first opened its doors in 1970 and has since flourished and grown into a multi-generational family-owned and operated enterprise, with three dealerships throughout the Houston area. Driven by his entrepreneurial spirit, Mr. Haas purchased his first two appliance businesses at the ages of 22 and 27. At the age of 30, he sold his appliance businesses and used his savings to begin buying and selling cars. Over the last 50 years, his hard work, determination, and vision have made Fred Haas a perennial leader in both sales and customer service.